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Fido, a Novel AMPylation Domain Common to Fic, Doc, and AvrB
BACKGROUND: The Vibrio parahaemolyticus type III secreted effector VopS contains a fic domain that covalently modifies Rho GTPase threonine with AMP to inhibit downstream signaling events in host cells. The VopS fic domain includes a conserved sequence motif (HPFx[D/E]GN[G/K]R) that contributes to A...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2686095/ https://www.ncbi.nlm.nih.gov/pubmed/19503829 http://dx.doi.org/10.1371/journal.pone.0005818 |