Rab27a and MyRIP regulate the amount and multimeric state of VWF released from endothelial cells

Endothelial cells contain cigar-shaped secretory organelles called Weibel-Palade bodies (WPBs) that play a crucial role in both hemostasis and the initiation of inflammation. The major cargo protein of WPBs is von Willebrand factor (VWF). In unstimulated cells, this protein is stored in a highly mul...

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Detalles Bibliográficos
Autores principales: Nightingale, Thomas D., Pattni, Krupa, Hume, Alistair N., Seabra, Miguel C., Cutler, Daniel F.
Formato: Texto
Lenguaje:English
Publicado: American Society of Hematology 2009
Materias:
Vascular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2686148/
https://www.ncbi.nlm.nih.gov/pubmed/19270261
http://dx.doi.org/10.1182/blood-2008-09-181206

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2686148/
https://www.ncbi.nlm.nih.gov/pubmed/19270261
http://dx.doi.org/10.1182/blood-2008-09-181206

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