Prion Protein Expression and Processing in Human Mononuclear Cells: The Impact of the Codon 129 Prion Gene Polymorphism

BACKGROUND: So far, all clinical cases of new variant Creutzfeldt-Jakob disease (vCJD), thought to result from the Bovine Spongiform Encephalopathy (BSE) prion agent, have shown Methionine–Methionine (M/M) homozygosity at the M129V polymorphism of the PRNP gene. Although established, this relationsh...

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Detalles Bibliográficos
Autores principales: Segarra, Christiane, Lehmann, Sylvain, Coste, Joliette
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2686158/
https://www.ncbi.nlm.nih.gov/pubmed/19495414
http://dx.doi.org/10.1371/journal.pone.0005796

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2686158/
https://www.ncbi.nlm.nih.gov/pubmed/19495414
http://dx.doi.org/10.1371/journal.pone.0005796

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