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Convergence of IL-1β and VDR Activation Pathways in Human TLR2/1-Induced Antimicrobial Responses

Antimicrobial effector mechanisms are central to the function of the innate immune response in host defense against microbial pathogens. In humans, activation of Toll-like receptor 2/1 (TLR2/1) on monocytes induces a vitamin D dependent antimicrobial activity against intracellular mycobacteria. Here...

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Detalles Bibliográficos
Autores principales: Liu, Philip T., Schenk, Mirjam, Walker, Valencia P., Dempsey, Paul W., Kanchanapoomi, Melissa, Wheelwright, Matthew, Vazirnia, Aria, Zhang, Xiaoran, Steinmeyer, Andreas, Zügel, Ulrich, Hollis, Bruce W., Cheng, Genhong, Modlin, Robert L.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2686169/
https://www.ncbi.nlm.nih.gov/pubmed/19503839
http://dx.doi.org/10.1371/journal.pone.0005810