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Convergence of IL-1β and VDR Activation Pathways in Human TLR2/1-Induced Antimicrobial Responses
Antimicrobial effector mechanisms are central to the function of the innate immune response in host defense against microbial pathogens. In humans, activation of Toll-like receptor 2/1 (TLR2/1) on monocytes induces a vitamin D dependent antimicrobial activity against intracellular mycobacteria. Here...
Autores principales: | Liu, Philip T., Schenk, Mirjam, Walker, Valencia P., Dempsey, Paul W., Kanchanapoomi, Melissa, Wheelwright, Matthew, Vazirnia, Aria, Zhang, Xiaoran, Steinmeyer, Andreas, Zügel, Ulrich, Hollis, Bruce W., Cheng, Genhong, Modlin, Robert L. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2686169/ https://www.ncbi.nlm.nih.gov/pubmed/19503839 http://dx.doi.org/10.1371/journal.pone.0005810 |
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