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N-Myc Regulates Expression of Pluripotency Genes in Neuroblastoma Including lif, klf2, klf4, and lin28b

myc genes are best known for causing tumors when overexpressed, but recent studies suggest endogenous myc regulates pluripotency and self-renewal of stem cells. For example, N-myc is associated with a number of tumors including neuroblastoma, but also plays a central role in the function of normal n...

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Detalles Bibliográficos
Autores principales: Cotterman, Rebecca, Knoepfler, Paul S.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2686170/
https://www.ncbi.nlm.nih.gov/pubmed/19495417
http://dx.doi.org/10.1371/journal.pone.0005799