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Distinct phosphorylation requirements regulate cortactin activation by Tir(EPEC )and its binding to N-WASP
BACKGROUND: Cortactin activates the actin-related 2/3 (Arp2/3) complex promoting actin polymerization to remodel cell architecture in multiple processes (e.g. cell migration, membrane trafficking, invadopodia formation etc.). Moreover, it was called the Achilles' heel of the actin cytoskeleton...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2009
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2686683/ https://www.ncbi.nlm.nih.gov/pubmed/19419567 http://dx.doi.org/10.1186/1478-811X-7-11 |