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Distinct phosphorylation requirements regulate cortactin activation by Tir(EPEC )and its binding to N-WASP
BACKGROUND: Cortactin activates the actin-related 2/3 (Arp2/3) complex promoting actin polymerization to remodel cell architecture in multiple processes (e.g. cell migration, membrane trafficking, invadopodia formation etc.). Moreover, it was called the Achilles' heel of the actin cytoskeleton...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2686683/ https://www.ncbi.nlm.nih.gov/pubmed/19419567 http://dx.doi.org/10.1186/1478-811X-7-11 |