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NuMA is required for proper spindle assembly and chromosome alignment in prometaphase

BACKGROUND: NuMA is a protein that has been previously shown to play a role in focusing microtubules at the mitotic spindle poles. However, most previous work relies on experimental methods that might cause dominant side effects on spindle formation, such as microinjection of antibodies, overexpress...

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Detalles Bibliográficos
Autores principales: Haren, Laurence, Gnadt, Nicole, Wright, Michel, Merdes, Andreas
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2686716/
https://www.ncbi.nlm.nih.gov/pubmed/19400937
http://dx.doi.org/10.1186/1756-0500-2-64