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Losartan, an angiotensin-II type 1 receptor blocker, attenuates the liver fibrosis development of non-alcoholic steatohepatitis in the rat

BACKGROUND: Apart from simple steatosis, the non-alcoholic steatohepatitis (NASH) can progress into liver fibrosis and cirrhosis. To date, however, no widely accepted therapeutic modalities have been established against NASH in the clinical practice. To find out promising new therapeutic agents, it...

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Detalles Bibliográficos
Autores principales: Yoshiji, Hitoshi, Noguchi, Ryuichi, Ikenaka, Yasuhide, Namisaki, Tadashi, Kitade, Mitsuteru, Kaji, Kosuke, Shirai, Yusaku, Yoshii, Junichi, Yanase, Koji, Yamazaki, Masaharu, Tsujimoto, Tatsuhiro, Kawaratani, Hideto, Akahane, Takemi, Aihara, Yosuke, Fukui, Hiroshi
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2686718/
https://www.ncbi.nlm.nih.gov/pubmed/19416517
http://dx.doi.org/10.1186/1756-0500-2-70