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Losartan, an angiotensin-II type 1 receptor blocker, attenuates the liver fibrosis development of non-alcoholic steatohepatitis in the rat
BACKGROUND: Apart from simple steatosis, the non-alcoholic steatohepatitis (NASH) can progress into liver fibrosis and cirrhosis. To date, however, no widely accepted therapeutic modalities have been established against NASH in the clinical practice. To find out promising new therapeutic agents, it...
Autores principales: | Yoshiji, Hitoshi, Noguchi, Ryuichi, Ikenaka, Yasuhide, Namisaki, Tadashi, Kitade, Mitsuteru, Kaji, Kosuke, Shirai, Yusaku, Yoshii, Junichi, Yanase, Koji, Yamazaki, Masaharu, Tsujimoto, Tatsuhiro, Kawaratani, Hideto, Akahane, Takemi, Aihara, Yosuke, Fukui, Hiroshi |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2686718/ https://www.ncbi.nlm.nih.gov/pubmed/19416517 http://dx.doi.org/10.1186/1756-0500-2-70 |
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