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High-resolution DNA copy number and gene expression analyses distinguish chromophobe renal cell carcinomas and renal oncocytomas

BACKGROUND: The diagnosis of benign renal oncocytomas (RO) and chromophobe renal cell carcinomas (RCC) based on their morphology remains uncertain in several cases. METHODS: We have applied Affymetrix GeneChip Mapping 250 K NspI high-density oligoarrays to identify small genomic alterations, which m...

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Detalles Bibliográficos
Autores principales: Yusenko, Maria V, Kuiper, Roland P, Boethe, Tamas, Ljungberg, Börje, van Kessel, Ad Geurts, Kovacs, Gyula
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2686725/
https://www.ncbi.nlm.nih.gov/pubmed/19445733
http://dx.doi.org/10.1186/1471-2407-9-152