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Both Ca(2+ )and Zn(2+ )are essential for S100A12 protein oligomerization and function

BACKGROUND: Human S100A12 is a member of the S100 family of EF-hand calcium-modulated proteins that are associated with many diseases including cancer, chronic inflammation and neurological disorders. S100A12 is an important factor in host/parasite defenses and in the inflammatory response. Like sev...

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Detalles Bibliográficos
Autores principales: Moroz, Olga V, Burkitt, Will, Wittkowski, Helmut, He, Wei, Ianoul, Anatoli, Novitskaya, Vera, Xie, Jingjing, Polyakova, Oxana, Lednev, Igor K, Shekhtman, Alexander, Derrick, Peter J, Bjoerk, Per, Foell, Dirk, Bronstein, Igor B
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2686732/
https://www.ncbi.nlm.nih.gov/pubmed/19386136
http://dx.doi.org/10.1186/1471-2091-10-11