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Both Ca(2+ )and Zn(2+ )are essential for S100A12 protein oligomerization and function
BACKGROUND: Human S100A12 is a member of the S100 family of EF-hand calcium-modulated proteins that are associated with many diseases including cancer, chronic inflammation and neurological disorders. S100A12 is an important factor in host/parasite defenses and in the inflammatory response. Like sev...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2686732/ https://www.ncbi.nlm.nih.gov/pubmed/19386136 http://dx.doi.org/10.1186/1471-2091-10-11 |