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No effects of bosentan on microvasculature in patients with limited cutaneous systemic sclerosis
The endothelium-derived vasoconstrictor molecule endothelin-1 (ET-1) has been suggested to play a role in the pathogenesis of Raynaud’s phenomenon (RP) and systemic sclerosis (SSc). We studied the effect of bosentan on microvascular structure and function in patients with RP secondary to limited cut...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2686804/ https://www.ncbi.nlm.nih.gov/pubmed/19350343 http://dx.doi.org/10.1007/s10067-009-1157-4 |