Activation of the P2X7 ion channel by soluble and covalently bound ligands

The homotrimeric P2X7 purinergic receptor has sparked interest because of its capacity to sense adenosine triphosphate (ATP) and nicotinamide adenine dinucleotide (NAD) released from cells and to induce calcium signaling and cell death. Here, we examine the response of arginine mutants of P2X7 to so...

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Detalles Bibliográficos
Autores principales: Schwarz, Nicole, Fliegert, Ralf, Adriouch, Sahil, Seman, Michel, Guse, Andreas H., Haag, Friedrich, Koch-Nolte, Friedrich
Formato: Texto
Lenguaje:English
Publicado: Springer Netherlands 2009
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2686825/
https://www.ncbi.nlm.nih.gov/pubmed/19255877
http://dx.doi.org/10.1007/s11302-009-9135-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2686825/
https://www.ncbi.nlm.nih.gov/pubmed/19255877
http://dx.doi.org/10.1007/s11302-009-9135-5

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