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The P2X(7) receptor–pannexin connection to dye uptake and IL-1β release

The P2X(7) receptor (P2X(7)R) is uniquely associated with two distinct cellular responses: activation of a dye-permeable pathway allowing passage of molecules up to 900 Da and rapid release of the pro-inflammatory cytokine, interleukin-1β (IL-1β), from activated macrophage. How this dye uptake path...

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Detalles Bibliográficos
Autores principales: Pelegrin, Pablo, Surprenant, Annmarie
Formato: Texto
Lenguaje:English
Publicado: Springer Netherlands 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2686830/
https://www.ncbi.nlm.nih.gov/pubmed/19212823
http://dx.doi.org/10.1007/s11302-009-9141-7