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Effect of Dexrazoxane and Amifostine on the Vertebral Bone Quality of Doxorubicin Treated Male Rats

Doxorubicin (DOX) is widely used in combination cocktails for treatment of childhood hematological cancers and solid tumors. A major factor limiting DOX usage is DOX-induced cardiotoxicity. However, it is not known whether protectants like dexrazoxane (DXR) and amifostine (AMF) can prevent DOX-media...

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Detalles Bibliográficos
Autores principales: Mwale, F, Marguier, G, Ouellet, J.A, Petit, A, Epure, L.M, Antoniou, J, Chalifour, L.E
Formato: Texto
Lenguaje:English
Publicado: Bentham Open 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2687116/
https://www.ncbi.nlm.nih.gov/pubmed/19478935
http://dx.doi.org/10.2174/1874325000802010115