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p53 regulates mtDNA copy number and mitocheckpoint pathway

BACKGROUND: We previously hypothesized a role for mitochondria damage checkpoint (mito-checkpoint) in maintaining the mitochondrial integrity of cells. Consistent with this hypothesis, defects in mitochondria have been demonstrated to cause genetic and epigenetic changes in the nuclear DNA, resistan...

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Detalles Bibliográficos
Autores principales:	Kulawiec, Mariola, Ayyasamy, Vanniarajan, Singh, Keshav K.
Formato:	Texto
Lenguaje:	English
Publicado:	Medknow Publications 2009
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2687143/ https://www.ncbi.nlm.nih.gov/pubmed/19439913 http://dx.doi.org/10.4103/1477-3163.50893

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