Down-regulation of sfrp1 in a mammary epithelial cell line promotes the development of a cd44(high)/cd24(low )population which is invasive and resistant to anoikis

BACKGROUND: The Wnt family of secreted proteins is implicated in the regulation of cell fate during development, as well as in cell proliferation, morphology, and migration. Aberrant activation of the Wnt/β-catenin signaling pathway leads to the development of several human cancers, including breast...

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Detalles Bibliográficos
Autores principales: Gauger, Kelly J, Hugh, Jeremy M, Troester, Melissa A, Schneider, Sallie Smith
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2687411/
https://www.ncbi.nlm.nih.gov/pubmed/19422694
http://dx.doi.org/10.1186/1475-2867-9-11

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2687411/
https://www.ncbi.nlm.nih.gov/pubmed/19422694
http://dx.doi.org/10.1186/1475-2867-9-11

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