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Down-regulation of sfrp1 in a mammary epithelial cell line promotes the development of a cd44(high)/cd24(low )population which is invasive and resistant to anoikis
BACKGROUND: The Wnt family of secreted proteins is implicated in the regulation of cell fate during development, as well as in cell proliferation, morphology, and migration. Aberrant activation of the Wnt/β-catenin signaling pathway leads to the development of several human cancers, including breast...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2687411/ https://www.ncbi.nlm.nih.gov/pubmed/19422694 http://dx.doi.org/10.1186/1475-2867-9-11 |