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Transduction of rat pancreatic islets with pseudotyped adeno-associated virus vectors

BACKGROUND: Pancreatic islet transplantation is a promising treatment for type I diabetes mellitus, but current immunosuppressive strategies do not consistently provide long-term survival of transplanted islets. We are therefore investigating the use of adeno-associated viruses (AAVs) as gene therap...

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Detalles Bibliográficos
Autores principales: Craig, Anthony T, Gavrilova, Oksana, Dwyer, Nancy K, Jou, William, Pack, Stephanie, Liu, Eric, Pechhold, Klaus, Schmidt, Michael, McAlister, Victor J, Chiorini, John A, Blanchette-Mackie, E Joan, Harlan, David M, Owens, Roland A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2687429/
https://www.ncbi.nlm.nih.gov/pubmed/19450275
http://dx.doi.org/10.1186/1743-422X-6-61