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Small local variations in B-form DNA lead to a large variety of global geometries which can accommodate most DNA-binding protein motifs

BACKGROUND: An important question of biological relevance is the polymorphism of the double-helical DNA structure in its free form, and the changes that it undergoes upon protein-binding. We have analysed a database of free DNA crystal structures to assess the inherent variability of the free DNA st...

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Detalles Bibliográficos
Autores principales: Marathe, Arvind, Karandur, Deepti, Bansal, Manju
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2687451/
https://www.ncbi.nlm.nih.gov/pubmed/19393049
http://dx.doi.org/10.1186/1472-6807-9-24