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Small local variations in B-form DNA lead to a large variety of global geometries which can accommodate most DNA-binding protein motifs
BACKGROUND: An important question of biological relevance is the polymorphism of the double-helical DNA structure in its free form, and the changes that it undergoes upon protein-binding. We have analysed a database of free DNA crystal structures to assess the inherent variability of the free DNA st...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2687451/ https://www.ncbi.nlm.nih.gov/pubmed/19393049 http://dx.doi.org/10.1186/1472-6807-9-24 |