Safety and feasibility of switching from phenytoin to levetiracetam monotherapy for glioma-related seizure control following craniotomy: a randomized phase II pilot study

Seizures are common in patients with gliomas, and phenytoin (PHT) is frequently used to control tumor-related seizures. PHT, however, has many undesirable side effects (SEs) and drug interactions with glioma chemotherapy. Levetiracetam (LEV) is a newer antiepileptic drug (AED) with fewer SEs and ess...

Descripción completa

Detalles Bibliográficos
Autores principales: Lim, Daniel A., Tarapore, Phiroz, Chang, Edward, Burt, Marlene, Chakalian, Lenna, Barbaro, Nicholas, Chang, Susan, Lamborn, Kathleen R., McDermott, Michael W.
Formato: Texto
Lenguaje:English
Publicado: Springer US 2009
Materias:
Clinical Study - Patient Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2687520/
https://www.ncbi.nlm.nih.gov/pubmed/19169651
http://dx.doi.org/10.1007/s11060-008-9781-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2687520/
https://www.ncbi.nlm.nih.gov/pubmed/19169651
http://dx.doi.org/10.1007/s11060-008-9781-4

Ejemplares similares