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Polymorphism in the promoter region of the klotho gene (G-395A) is associated with early dysfunction in vascular access in hemodialysis patients

BACKGROUND/AIMS: Vascular access dysfunction is an important cause of morbidity and mortality in hemodialysis (HD) patients. Recent studies have shown that a klotho gene mutation is related to endothelial dysfunction, thrombosis, and arteriosclerosis, which are regarded as causes of vascular access...

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Detalles Bibliográficos
Autores principales: Kim, Youngsu, Jeong, Sun Joo, Lee, Hyung Suk, Kim, Eun Jung, Song, Young Rim, Kim, Sung Gyun, Oh, Ji Eun, Lee, Young Ki, Seo, Jang Won, Yoon, Jong Woo, Koo, Ja-Ryong, Kim, Hyung Jik, Noh, Jung Woo, Park, Seung Ho
Formato: Texto
Lenguaje:English
Publicado: The Korean Association of Internal Medicine 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2687682/
https://www.ncbi.nlm.nih.gov/pubmed/19119257
http://dx.doi.org/10.3904/kjim.2008.23.4.201