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CD146 expression is associated with a poor prognosis in human breast tumors and with enhanced motility in breast cancer cell lines

INTRODUCTION: Metastasis is a complex process involving loss of adhesion, migration, invasion and proliferation of cancer cells. Cell adhesion molecules play a pivotal role in this phenomenon by regulating cell–cell and cell–matrix interactions. CD146 (MCAM) is associated with an advanced tumor stag...

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Detalles Bibliográficos
Autores principales: Zabouo, Gwladys, Imbert, Anne-Marie, Jacquemier, Jocelyne, Finetti, Pascal, Moreau, Thomas, Esterni, Benjamin, Birnbaum, Daniel, Bertucci, François, Chabannon, Christian
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2687703/
https://www.ncbi.nlm.nih.gov/pubmed/19123925
http://dx.doi.org/10.1186/bcr2215