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Assessing the Neuronal Serotonergic Target-based Antidepressant Stratagem: Impact of In Vivo Interaction Studies and Knockout Models

Depression remains a challenge in the field of affective neuroscience, despite a steady research progress. Six out of nine basic antidepressant mechanisms rely on serotonin neurotransmitter system. Preclinical studies have demonstrated the significance of serotonin receptors (5-HT(1-3,6,7)), its sig...

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Detalles Bibliográficos
Autores principales: Rajkumar, R, Mahesh, R
Formato: Texto
Lenguaje:English
Publicado: Bentham Science Publishers Ltd. 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2687932/
https://www.ncbi.nlm.nih.gov/pubmed/19506722
http://dx.doi.org/10.2174/157015908785777256