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From disease ontology to disease-ontology lite: statistical methods to adapt a general-purpose ontology for the test of gene-ontology associations

Subjective methods have been reported to adapt a general-purpose ontology for a specific application. For example, Gene Ontology (GO) Slim was created from GO to generate a highly aggregated report of the human-genome annotation. We propose statistical methods to adapt the general purpose, OBO Found...

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Detalles Bibliográficos
Autores principales: Du, Pan, Feng, Gang, Flatow, Jared, Song, Jie, Holko, Michelle, Kibbe, Warren A., Lin, Simon M.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2687947/
https://www.ncbi.nlm.nih.gov/pubmed/19478018
http://dx.doi.org/10.1093/bioinformatics/btp193