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In silico miRNA prediction in metazoan genomes: balancing between sensitivity and specificity

BACKGROUND: MicroRNAs (miRNAs), short ~21-nucleotide RNA molecules, play an important role in post-transcriptional regulation of gene expression. The number of known miRNA hairpins registered in the miRBase database is rapidly increasing, but recent reports suggest that many miRNAs with restricted t...

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Detalles Bibliográficos
Autores principales: van der Burgt, Ate, Fiers, Mark WJE, Nap, Jan-Peter, van Ham, Roeland CHJ
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688010/
https://www.ncbi.nlm.nih.gov/pubmed/19405940
http://dx.doi.org/10.1186/1471-2164-10-204