MARCO, TLR2, and CD14 Are Required for Macrophage Cytokine Responses to Mycobacterial Trehalose Dimycolate and Mycobacterium tuberculosis

Virtually all of the elements of Mycobacterium tuberculosis (Mtb) pathogenesis, including pro-inflammatory cytokine production, granuloma formation, cachexia, and mortality, can be induced by its predominant cell wall glycolipid, trehalose 6,6′-dimycolate (TDM/cord factor). TDM mediates these potent...

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Detalles Bibliográficos
Autores principales: Bowdish, Dawn M. E., Sakamoto, Kaori, Kim, Mi-Jeong, Kroos, Mariliis, Mukhopadhyay, Subhankar, Leifer, Cynthia A., Tryggvason, Karl, Gordon, Siamon, Russell, David G.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688075/
https://www.ncbi.nlm.nih.gov/pubmed/19521507
http://dx.doi.org/10.1371/journal.ppat.1000474

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688075/
https://www.ncbi.nlm.nih.gov/pubmed/19521507
http://dx.doi.org/10.1371/journal.ppat.1000474

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