Cargando…

MARCO, TLR2, and CD14 Are Required for Macrophage Cytokine Responses to Mycobacterial Trehalose Dimycolate and Mycobacterium tuberculosis

Virtually all of the elements of Mycobacterium tuberculosis (Mtb) pathogenesis, including pro-inflammatory cytokine production, granuloma formation, cachexia, and mortality, can be induced by its predominant cell wall glycolipid, trehalose 6,6′-dimycolate (TDM/cord factor). TDM mediates these potent...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bowdish, Dawn M. E., Sakamoto, Kaori, Kim, Mi-Jeong, Kroos, Mariliis, Mukhopadhyay, Subhankar, Leifer, Cynthia A., Tryggvason, Karl, Gordon, Siamon, Russell, David G.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688075/ https://www.ncbi.nlm.nih.gov/pubmed/19521507 http://dx.doi.org/10.1371/journal.ppat.1000474

Ejemplares similares

Defining the conformation of human mincle that interacts with mycobacterial trehalose dimycolate
por: Jégouzo, Sabine A F, et al.
Publicado: (2014)

Direct recognition of the mycobacterial glycolipid, trehalose dimycolate, by C-type lectin Mincle
por: Ishikawa, Eri, et al.
Publicado: (2009)

Neutrophils Promote Mycobacterial Trehalose Dimycolate-Induced Lung Inflammation via the Mincle Pathway
por: Lee, Wook-Bin, et al.
Publicado: (2012)

Sophora flavescens protects against mycobacterial Trehalose Dimycolate-induced lung granuloma by inhibiting inflammation and infiltration of macrophages
por: Liu, Dehua, et al.
Publicado: (2018)

A FRET-Based Fluorogenic Trehalose Dimycolate Analogue for Probing Mycomembrane-Remodeling Enzymes of Mycobacteria
por: Holmes, Nathan J., et al.
Publicado: (2019)

Modulation of Trehalose Dimycolate and Immune System by Rv0774c Protein Enhanced the Intracellular Survival of Mycobacterium smegmatis in Human Macrophages Cell Line
por: Kumar, Arbind, et al.
Publicado: (2017)

Genetic variants of MARCO are associated with susceptibility to pulmonary tuberculosis in a Gambian population
por: Bowdish, Dawn ME, et al.
Publicado: (2013)

Trehalose dimycolate interferes with FcγR-mediated phagosome maturation through Mincle, SHP-1 and FcγRIIB signalling
por: Patin, Emmanuel C., et al.
Publicado: (2017)

TLR9 is important for protection against intestinal damage and for intestinal repair
por: II, William Alfred Rose, et al.
Publicado: (2012)

A Naturally-Occurring Transcript Variant of MARCO Reveals the SRCR Domain is Critical for Function
por: Novakowski, Kyle E., et al.
Publicado: (2016)

TLR9 regulates Th1 responses and cooperates with TLR2 in mediating optimal resistance to Mycobacterium tuberculosis
por: Bafica, Andre, et al.
Publicado: (2005)

Trehalose Recycling Promotes Energy-Efficient Biosynthesis of the Mycobacterial Cell Envelope
por: Pohane, Amol Arunrao, et al.
Publicado: (2021)

Macrophage Pattern Recognition Receptors in Immunity, Homeostasis and Self Tolerance
por: Mukhopadhyay, Subhankar, et al.
Publicado: (2009)

Molecular recognition of trehalose and trehalose analogues by Mycobacterium tuberculosis LpqY-SugABC
por: Liang, Jingxi, et al.
Publicado: (2023)

Molecular regulation of TLR signaling in health and disease: mechano-regulation of macrophages and TLR signaling
por: Gruber, Erika J, et al.
Publicado: (2020)

Structural basis of trehalose recognition by the mycobacterial LpqY-SugABC transporter
por: Furze, Christopher M., et al.
Publicado: (2021)

An apolipoprotein A-I mimetic targets scavenger receptor A on tumor-associated macrophages: A prospective anticancer treatment?
por: Neyen, Claudine, et al.
Publicado: (2013)

Mycobacterial glycolipids di-O-acylated trehalose and tri-O-acylated trehalose downregulate inducible nitric oxide synthase and nitric oxide production in macrophages
por: Espinosa-Cueto, Patricia, et al.
Publicado: (2015)

Growth Temperature, Trehalose, and Susceptibility to Heat in Mycobacterium avium
por: Guenette, Simonne, et al.
Publicado: (2020)

Mycobacterial glycolipid Di-O-acyl trehalose promotes a tolerogenic profile in dendritic cells
por: Magallanes-Puebla, Alejandro, et al.
Publicado: (2018)

Asymmetric Total Synthesis of Mycobacterial Diacyl Trehaloses Demonstrates a Role for Lipid Structure in Immunogenicity
por: Holzheimer, Mira, et al.
Publicado: (2020)

The Scavenger Receptor MARCO Modulates TLR-Induced Responses in Dendritic Cells
por: Kissick, Haydn T., et al.
Publicado: (2014)

The Scavenger Receptor MARCO Is Required for Lung Defense against Pneumococcal Pneumonia and Inhaled Particles
por: Arredouani, Mohamed, et al.
Publicado: (2004)

Mycobacterium tuberculosis Rv2387 Facilitates Mycobacterial Survival by Silencing TLR2/p38/JNK Signaling
por: Li, Wu, et al.
Publicado: (2022)

Over-Expression of the Mycobacterial Trehalose-Phosphate Phosphatase OtsB2 Results in a Defect in Macrophage Phagocytosis Associated with Increased Mycobacterial-Macrophage Adhesion
por: Li, Hao, et al.
Publicado: (2016)

Role of the Scavenger Receptor MARCO in Alveolar Macrophage Binding of Unopsonized Environmental Particles
por: Palecanda, Aiyappa, et al.
Publicado: (1999)

Mycobacterium abscessus: Shapeshifter of the Mycobacterial World
por: Ryan, Keenan, et al.
Publicado: (2018)

Multifunctional role of dextran sulfate sodium for in vivo modeling of intestinal diseases
por: Rose, William A, et al.
Publicado: (2012)

PPE51 mediates uptake of trehalose across the mycomembrane of Mycobacterium tuberculosis
por: Babu Sait, Mohammed Rizwan, et al.
Publicado: (2022)

Trehalose limits opportunistic mycobacterial survival during HIV co-infection by reversing HIV-mediated autophagy block
por: Sharma, Vartika, et al.
Publicado: (2020)

Synthetic mycobacterial diacyl trehaloses reveal differential recognition by human T cell receptors and the C-type lectin Mincle
por: Reijneveld, Josephine F., et al.
Publicado: (2021)

Age‐dependent effect between MARCO and TLR4 on PMMA particle phagocytosis by macrophages
por: Yamada, Chiaki, et al.
Publicado: (2019)

Interrogation of the Pathogen Box reveals small molecule ligands against the mycobacterial trehalose transporter LpqY-SugABC
por: Radhakrishnan, Anjana, et al.
Publicado: (2022)

The role of myeloid receptors on murine plasmacytoid dendritic cells in induction of type I interferon
por: Seeds, Rosalind E., et al.
Publicado: (2011)

Adipoclast: a multinucleated fat-eating macrophage
por: Olona, Antoni, et al.
Publicado: (2021)

A Novel Trehalose Synthase for the Production of Trehalose and Trehalulose
por: Agarwal, Neera, et al.
Publicado: (2021)

Mycobacterial panniculitis caused by Mycobacterium thermoresistibile in a cat
por: Vishkautsan, Polina, et al.
Publicado: (2016)

Marco Aurelio
por: Marco Aurelio, Emperador de Roma, 121-180
Publicado: (1968)

Marco Polo /
por: Collis, Maurice, 1889-1973
Publicado: (1984)

Yo, Marcos /
por: Marcos, subcomandante
Publicado: (1994)

Cannot write session to /tmp/vufind_sessions/sess_f8fkfvanpfhcotfci8258r691c