A Kinship-Based Modification of the Armitage Trend Test to Address Hidden Population Structure and Small Differential Genotyping Errors

BACKGROUND/AIMS: We propose a modification of the well-known Armitage trend test to address the problems associated with hidden population structure and hidden relatedness in genome-wide case-control association studies. METHODS: The new test adopts beneficial traits from three existing testing stra...

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Detalles Bibliográficos
Autores principales: Rakovski, Cyril S., Stram, Daniel O.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688076/
https://www.ncbi.nlm.nih.gov/pubmed/19503792
http://dx.doi.org/10.1371/journal.pone.0005825

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688076/
https://www.ncbi.nlm.nih.gov/pubmed/19503792
http://dx.doi.org/10.1371/journal.pone.0005825

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