Cargando…
A Kinship-Based Modification of the Armitage Trend Test to Address Hidden Population Structure and Small Differential Genotyping Errors
BACKGROUND/AIMS: We propose a modification of the well-known Armitage trend test to address the problems associated with hidden population structure and hidden relatedness in genome-wide case-control association studies. METHODS: The new test adopts beneficial traits from three existing testing stra...
| Autores principales: | , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2009
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688076/ https://www.ncbi.nlm.nih.gov/pubmed/19503792 http://dx.doi.org/10.1371/journal.pone.0005825 |