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Lymphocytes, apoptosis and sepsis: making the jump from mice to humans

Sepsis is an important clinical problem with a mortality rate of 20% to 30%. Lymphocyte apoptosis has been recognized as an important step in the pathogenesis of experimental sepsis, by inducing a state of 'immune paralysis' that renders the host vulnerable to invading pathogens. The impor...

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Detalles Bibliográficos
Autores principales: Lang, John D, Matute-Bello, Gustavo
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688100/
https://www.ncbi.nlm.nih.gov/pubmed/19216722
http://dx.doi.org/10.1186/cc7144