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Recombinant human activated protein C in acute lung injury: what is the role of bronchial circulation?

Impairment of the protein C pathway plays a central role in the pathogenesis of sepsis. Treatment with recombinant human activated protein C (rhAPC) has been reported to increase survival from severe sepsis. Protein C levels also decrease markedly in acute lung injury, of both septic and nonseptic o...

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Detalles Bibliográficos
Autores principales: Maybauer, Marc O, Traber, Daniel L, Maybauer, Dirk M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688104/
https://www.ncbi.nlm.nih.gov/pubmed/19226431
http://dx.doi.org/10.1186/cc7155