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Novel polymorphism of interleukin-18 associated with greater inflammation after cardiac surgery

INTRODUCTION: Interleukin (IL)-18 is a key modulator of the cytokine response that leads to organ dysfunction and prolonged intensive care unit (ICU) stay after cardiopulmonary bypass surgery. We hypothesised that variation in the pro-inflammatory gene IL-18 is associated with adverse clinical outco...

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Detalles Bibliográficos
Autores principales: Shaw, David M, Sutherland, Ainsley M, Russell, James A, Lichtenstein, Samuel V, Walley, Keith R
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688121/
https://www.ncbi.nlm.nih.gov/pubmed/19178691
http://dx.doi.org/10.1186/cc7698