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Cardiac force-frequency relationship and frequency-dependent acceleration of relaxation are impaired in LPS-treated rats

INTRODUCTION: Frequency-dependent acceleration of relaxation (FDAR) ensures appropriate ventricular filling at high heart rates and results from accelerated sarcoplasmic/endoplasmic reticulum calcium ATPase (SERCA) activity independent of calcium removal from the cell. Because lipopolysaccharide (LP...

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Detalles Bibliográficos
Autores principales: Joulin, Olivier, Marechaux, Sylvestre, Hassoun, Sidi, Montaigne, David, Lancel, Steve, Neviere, Remi
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688131/
https://www.ncbi.nlm.nih.gov/pubmed/19196490
http://dx.doi.org/10.1186/cc7712