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Cardiac force-frequency relationship and frequency-dependent acceleration of relaxation are impaired in LPS-treated rats
INTRODUCTION: Frequency-dependent acceleration of relaxation (FDAR) ensures appropriate ventricular filling at high heart rates and results from accelerated sarcoplasmic/endoplasmic reticulum calcium ATPase (SERCA) activity independent of calcium removal from the cell. Because lipopolysaccharide (LP...
Autores principales: | Joulin, Olivier, Marechaux, Sylvestre, Hassoun, Sidi, Montaigne, David, Lancel, Steve, Neviere, Remi |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688131/ https://www.ncbi.nlm.nih.gov/pubmed/19196490 http://dx.doi.org/10.1186/cc7712 |
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