Hypoxia. Hypoxia in the pathogenesis of systemic sclerosis

Autoimmunity, microangiopathy and tissue fibrosis are hallmarks of systemic sclerosis (SSc). Vascular alterations and reduced capillary density decrease blood flow and impair tissue oxygenation in SSc. Oxygen supply is further reduced by accumulation of extracellular matrix (ECM), which increases di...

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Detalles Bibliográficos
Autores principales: Beyer, Christian, Schett, Georg, Gay, Steffen, Distler, Oliver, Distler, Jörg HW
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688169/
https://www.ncbi.nlm.nih.gov/pubmed/19473554
http://dx.doi.org/10.1186/ar2598

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688169/
https://www.ncbi.nlm.nih.gov/pubmed/19473554
http://dx.doi.org/10.1186/ar2598

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