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Vasoactive intestinal peptide inhibits TNF-α-induced apoptotic events in acinar cells from nonobese diabetic mice submandibular glands

INTRODUCTION: The role of apoptotic secretory epithelium as a pro-inflammatory triggering factor of exocrine dysfunction is currently explored in Sjogren's syndrome patients and in the nonobese diabetic (NOD) mouse model. Vasoactive intestinal peptide (VIP) has anti-inflammatory effects in vari...

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Detalles Bibliográficos
Autores principales: Calafat, Mario, Larocca, Luciana, Roca, Valeria, Hauk, Vanesa, Pregi, Nicolás, Nesse, Alcira, Pérez Leirós, Claudia
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688204/
https://www.ncbi.nlm.nih.gov/pubmed/19356238
http://dx.doi.org/10.1186/ar2671