Post-translational aging of proteins in osteoarthritic cartilage and synovial fluid as measured by isomerized aspartate

INTRODUCTION: Aging proteins undergo non-enzymatic post-translational modification, including isomerization and racemization. We hypothesized that cartilage with many long-lived components could accumulate non-enzymatically modified amino acids in the form of isomerized aspartate and that its libera...

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Detalles Bibliográficos
Autores principales: Catterall, Jonathan B, Barr, Daniel, Bolognesi, Michael, Zura, Robert D, Kraus, Virginia B
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688206/
https://www.ncbi.nlm.nih.gov/pubmed/19371408
http://dx.doi.org/10.1186/ar2675

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688206/
https://www.ncbi.nlm.nih.gov/pubmed/19371408
http://dx.doi.org/10.1186/ar2675

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