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Post-translational aging of proteins in osteoarthritic cartilage and synovial fluid as measured by isomerized aspartate
INTRODUCTION: Aging proteins undergo non-enzymatic post-translational modification, including isomerization and racemization. We hypothesized that cartilage with many long-lived components could accumulate non-enzymatically modified amino acids in the form of isomerized aspartate and that its libera...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688206/ https://www.ncbi.nlm.nih.gov/pubmed/19371408 http://dx.doi.org/10.1186/ar2675 |