Gene expression profiling in the synovium identifies a predictive signature of absence of response to adalimumab therapy in rheumatoid arthritis

INTRODUCTION: To identify markers and mechanisms of resistance to adalimumab therapy, we studied global gene expression profiles in synovial tissue specimens obtained from severe rheumatoid arthritis (RA) patients before and after initiation of treatment. METHODS: Paired synovial biopsies were obtai...

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Detalles Bibliográficos
Autores principales: Badot, Valérie, Galant, Christine, Nzeusseu Toukap, Adrien, Theate, Ivan, Maudoux, Anne-Lise, Van den Eynde, Benoît J, Durez, Patrick, Houssiau, Frédéric A, Lauwerys, Bernard R
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688209/
https://www.ncbi.nlm.nih.gov/pubmed/19389237
http://dx.doi.org/10.1186/ar2678

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688209/
https://www.ncbi.nlm.nih.gov/pubmed/19389237
http://dx.doi.org/10.1186/ar2678

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