Apigenin, a non-mutagenic dietary flavonoid, suppresses lupus by inhibiting autoantigen presentation for expansion of autoreactive Th1 and Th17 cells

INTRODUCTION: Lupus patients need alternatives to steroids and cytotoxic drugs. We recently found that apigenin, a non-mutagenic dietary flavonoid, can sensitize recurrently activated, normal human T cells to apoptosis by inhibiting nuclear factor-kappa-B (NF-κB)-regulated Bcl-x(L), cyclooxygenase 2...

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Detalles Bibliográficos
Autores principales: Kang, Hee-Kap, Ecklund, Diane, Liu, Michael, Datta, Syamal K
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688212/
https://www.ncbi.nlm.nih.gov/pubmed/19405952
http://dx.doi.org/10.1186/ar2682

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688212/
https://www.ncbi.nlm.nih.gov/pubmed/19405952
http://dx.doi.org/10.1186/ar2682

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