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No evidence of major effects in several Toll-like receptor gene polymorphisms in rheumatoid arthritis

INTRODUCTION: The objective was to study the potential genetic contribution of Toll-like receptor (TLR) genes in rheumatoid arthritis (RA). TLRs bind to pathogen-associated molecular patterns, and TLR genes influence both proinflammatory cytokine production and autoimmune responses. Host–pathogen in...

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Detalles Bibliográficos
Autores principales: Jaen, Olivier, Petit-Teixeira, Elisabeth, Kirsten, Holger, Ahnert, Peter, Semerano, Luca, Pierlot, Céline, Cornelis, Francois, Boissier, Marie-Christophe, Falgarone, Geraldine
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688235/
https://www.ncbi.nlm.nih.gov/pubmed/19134200
http://dx.doi.org/10.1186/ar2589