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Increased expression of FcγRI/CD64 on circulating monocytes parallels ongoing inflammation and nephritis in lupus
INTRODUCTION: The high-affinity receptor for IgG Fcγ/CD64 is critical for the development of lupus nephritis (LN). Cross-linking Fc receptor on recruited monocytes by IgG-containing immune complexes is a key step in immune-complex-mediated nephritis in systemic lupus erythematosus (SLE). The goal of...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688236/ https://www.ncbi.nlm.nih.gov/pubmed/19144150 http://dx.doi.org/10.1186/ar2590 |