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Dissection of a locus on mouse chromosome 5 reveals arthritis promoting and inhibitory genes

INTRODUCTION: In a cross between two mouse strains, the susceptible B10.RIII (H-2(r)) and resistant RIIIS/J (H-2(r)) strains, a locus on mouse chromosome 5 (Eae39) was previously shown to control experimental autoimmune encephalomyelitis (EAE). Recently, quantitative trait loci (QTL), linked to dise...

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Detalles Bibliográficos
Autores principales: Lindvall, Therese, Karlsson, Jenny, Holmdahl, Rikard, Andersson, Åsa
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688241/
https://www.ncbi.nlm.nih.gov/pubmed/20527086
http://dx.doi.org/10.1186/ar2597