Selective amplification of glucocorticoid anti-inflammatory activity through synergistic multi-target action of a combination drug

INTRODUCTION: Glucocorticoids are a mainstay of anti-inflammatory therapy, but significant adverse effects ultimately limit their utility. Previous efforts to design glucocorticoid structures with an increased therapeutic window have focused on dissociating anti-inflammatory transcriptional repressi...

Descripción completa

Detalles Bibliográficos
Autores principales: Zimmermann, Grant R, Avery, William, Finelli, Alyce L, Farwell, Melissa, Fraser, Christopher C, Borisy, Alexis A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688244/
https://www.ncbi.nlm.nih.gov/pubmed/19171052
http://dx.doi.org/10.1186/ar2602

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688244/
https://www.ncbi.nlm.nih.gov/pubmed/19171052
http://dx.doi.org/10.1186/ar2602

Ejemplares similares