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Antirheumatic drug response signatures in human chondrocytes: potential molecular targets to stimulate cartilage regeneration

INTRODUCTION: Rheumatoid arthritis (RA) leads to progressive destruction of articular cartilage. This study aimed to disclose major mechanisms of antirheumatic drug action on human chondrocytes and to reveal marker and pharmacological target genes that are involved in cartilage dysfunction and regen...

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Detalles Bibliográficos
Autores principales: Andreas, Kristin, Häupl, Thomas, Lübke, Carsten, Ringe, Jochen, Morawietz, Lars, Wachtel, Anja, Sittinger, Michael, Kaps, Christian
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688247/
https://www.ncbi.nlm.nih.gov/pubmed/19192274
http://dx.doi.org/10.1186/ar2605