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The role of RNA folding free energy in the evolution of the polymerase genes of the influenza A virus

BACKGROUND: The influenza A virus genome is composed of eight single-stranded RNA segments of negative polarity. Although the hemagglutinin and neuraminidase genes are known to play a key role in host adaptation, the polymerase genes (which encode the polymerase segments PB2, PB1, PA) and the nucleo...

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Detalles Bibliográficos
Autores principales: Brower-Sinning, Rachel, Carter, Donald M, Crevar, Corey J, Ghedin, Elodie, Ross, Ted M, Benos, Panayiotis V
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688270/
https://www.ncbi.nlm.nih.gov/pubmed/19216739
http://dx.doi.org/10.1186/gb-2009-10-2-r18